Dr.ObGyn.One on Instagram: "Colonoscopy without sedation is not pain-free😅, but the sensation is usually described as pressure, stretching, and cramping, mainly due to air or CO₂ insufflation and looping of the colon. The intensity varies depending on individual pain sensitivity, anatomy, bowel preparation quality, and the endoscopist’s technique. With sedation, most centers use moderate (conscious) sedation, typically a combination of midazolam (benzodiazepine for anxiolysis and amnesia) and a