Combining reduced-dose olaparib with radium-223 improved rPFS in mCRPC patients, especially those without prior docetaxel and limited bone metastases. The combination's efficacy is based on mechanisms ...

The forum highlighted advancements in bladder cancer treatment, focusing on intravesical therapies, systemic immunotherapy, and clinical trials for NMIBC and MIBC. Integration of PD-1 inhibitors with ...

Enzalutamide plus ADT significantly improves 5-year overall survival in mHSPC, with a 30% reduction in death risk compared to placebo plus ADT. The survival benefit of enzalutamide is consistent ...

ARASTEP trial evaluates darolutamide plus ADT for high-risk biochemical recurrence of prostate cancer, focusing on radiologic progression-free survival (rPFS) by PSMA PET-CT. The study involves 970 ...

Dr Shore discussed the potential for ultra-low PSA response to serve as an end point in future clinical trials. He highlighted how this metric could potentially influence precision medicine approaches ...

"CAN-2409 immunotherapy could represent the first new therapy for men with localized prostate cancer in over 20 years," wrote the authors. Adding aglatimagene besadenovec (CAN-2409) to standard of ...

Prostate-specific membrane antigen (PSMA) expression in renal cell carcinoma (RCC) was an incidental finding but shows potential. Uncertainty regarding frequency of PSMA expression across RCC subtypes ...

Future Directions for Imaging in Kidney Cancer Main Discussion Topics: Potential for deep learning and artificial intelligence (AI) to extract additional information from imaging data sets Recognition ...

The survey examines urologists' treatment patterns and preferences for non–muscle invasive bladder cancer, providing valuable insights into current practices. Michael S. Cookson, MD, and Jason M.

Welcome back to Pearls & Perspectives! In this episode of Pearls & Perspectives, host Amy Pearlman, MD, sits down with Diane K. Newman, DNP, a nationally recognized expert in pelvic health, to explore ...

The ARANOTE study had sufficient Black male representation for meaningful comparative analysis. Safety data from other clinical trials show similar patterns. Real-world evidence corroborates safety in ...