EGPA-associated nasal polyposis should be managed with medically (ie, biologics, anti-inflammatory drugs, and topical corticosteroids) and, in some cases, surgery. Nasal polyposis associated with ...

Patients with GPP who experienced flares had higher hospitalization rates (12.2% vs 6.9%) compared to those who did not flare. Patients with generalized pustular psoriasis (GPP) who experience flares ...

Castleman disease and IgG4-RD have overlapping disease manifestations that can complicate the diagnostic process. A male patient initially suspected of having immunoglobulin G4-related disease ...

Women who desire to become pregnant should be counseled on the significance of alloimmunization as a substantial risk during pregnancy. A pregnant woman with hemolytic disease of the fetus and newborn ...

Although a biopsy is essential to diagnose IgG4-RD and AAV, in those cases in which a biopsy cannot be performed, clinical features and supportive imaging or laboratory data may provide important ...

About 61% of patients with ATTR-PN had at least 2 comorbidities. Patients with transthyretin amyloid polyneuropathy (ATTR-PN) have a high rate of comorbidities and substantial direct healthcare and ...

Pregnancies affected by multiple alloantibodies had significantly higher antibody titers and an increased need for intrauterine transfusion. Pregnancies complicated by multiple alloantibodies rather ...

In diagnosed cases of cutaneous mastocytosis, investigations to rule out systemic mastocytosis may be appropriate. A young child with a small chest lump and anemia was found to have cutaneous ...

The trial will test 4 doses of PVT201 in healthy volunteers and and the highest dose deemed safe and well tolerated in patients. A new phase 1 clinical trial testing the safety tolerability, ...

Although no patients presented with severe disease, GPP still imposed a substantial burden on quality of life. Associations between therapies and quality of life (QoL) scores differ substantially in ...

Children with achondroplasia seem to be more challenged in the anterior-posterior direction, which might be linked to an anterior-shifted pelvis. No difference was observed in bipedal static postural ...

The rapid onset and resolution of the pustular eruption upon discontinuation of isotretinoin further supported the diagnosis of AGEP. Isotretinoin has the potential to trigger acute generalized ...