Donatella Versace is giving up the creative reins of luxury fashion label Versace after nearly three decades, it was announced on Thursday, effectively ending the family's hold over the brand founded by her murdered brother.

Donatella Versace will step down as creative director of the luxury fashion house that bears her family name after nearly three decades and make way for Miu Miu designer Dario Vitale.

It’s the end of an era at the House of Medusa—and the start of a new one. On Thursday, Versace announced that Donatella Versace, the pure embodiment of the brand’s va-va-voom glamor, is stepping down as creative director after nearly three decades. Her successor is Dario Vitale, a rising star who was most recently the design director of Miu Miu.