The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

Today:Early fog in the far southwest clears quickly. Most areas stay dry with sunshine and variable cloud, though northern and northeastern regions may see isolated showers. Light winds overall, ...

Exploratory data analysis (EDA) is a prerequisite for all data science, as illustrated by the ubiquity of Jupyter notebooks, the preferred interface for EDA among data scientists. The operations ...

Over the past decade, significant advancements have been made in both DNA synthesis and sequencing technologies 1,2,3,4,5,6,7. These advancements have also led to the emergence of DNA-based data ...

DNA helicases use the energy of adenosine triphosphate hydrolysis to walk along and unwind DNA, making them essential for many cellular tasks. Still, key details of how they work are not well ...

Endoscopic imaging plays a very important role in the diagnosis and treatment of lesions. However, the imaging range of endoscopes is small, which may affect the doctors' judgment on the scope and ...

Chromatin profiling techniques, such as ChIP-seq 1, ATAC-seq 2, and Hi-C 3, have been widely used to study transcription factor binding 4, chromatin accessibility 5, and higher-order chromatin ...

As Artificial Intelligence (AI) continues to expand its reach, the demand for human control and the development of AI systems that adhere to our legal, ethical, and social values also grows. Many ...

Edited by Michael B. Eisen, Howard Hughes Medical Institute, University of California, Berkeley, CA, and accepted by the Editorial Board August 31, 2012 (received for review September 9, 2011) Despite ...