Medical Dialogues

Ancillary Medications Drive More Adverse Drug Effects in Rheumatologic Disorders Than DMARDs: Study

A large case-control study found that adverse drug effects in patients with autoimmune rheumatologic diseases were more ...
BMJ

Mouthguard use in youth ice hockey and the risk of concussion: nested case–control study of 315 cases

Correspondence to Dr Brent E Hagel, Department of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada; brent.hagel{at}albertahealthservices.ca Background ...
The Lancet

Circulating inflammatory and immune response proteins and endometrial cancer risk: a nested case-control study and Mendelian randomization analyses

eDepartment of Metabolism, Digestion & Reproduction - Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom fWest London Gynaecological Cancer Centre, Imperial ...
ahajournals.org

Recurrent Ischemic Stroke and Vaginal Estradiol in Women With Prior Ischemic Stroke: A Nationwide Nested Case-Control Study

Systemic estrogen replacement therapy is contraindicated in women with a history of ischemic stroke due to the risk of stroke recurrence. There are currently no published data available describing the ...
C&EN

Effects of Serum Insulin and Insulin-Like Growth Factor 1 Levels on the Association between Fetal Growth and Per- and Polyfluoroalkyl Substance Exposure Based on a Nested Case ...

Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk ...
thorax.bmj

Epigenome-wide association study of lung cancer among never smokers in two prospective cohorts in Shanghai, China

Background The aetiology of lung cancer among individuals who never smoked remains elusive, despite 15% of lung cancer cases in men and 53% in women worldwide being unrelated to smoking. Epigenetic ...
ascopubs.org

Risk factors for severe cancer chemotherapy toxicity in the outpatient setting: Results of a nested case control study using a novel patient cohort

Time interval between final protocol approval (FPA) and inclusion of the first patient into randomized clinical trials (RCTs) performed by the Central European Cooperative Oncology Group (CECOG): A 10 ...
BMJ

Combining high quality data with rigorous methods: emulation of a target trial using electronic health records and a nested case-control design

4 Department of Epidemiology, University of Washington, Seattle, WA, USA 5 Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA 6 ...
BMJ

Menopausal hormone therapy and dementia: nationwide, nested case-control study

Objectives To assess the association between use of menopausal hormone therapy and development of dementia according to type of hormone treatment, duration of use, and age at usage. Design Nationwide, ...
ascopubs.org

Risk Factors for Primary Bone Cancer After Childhood Cancer: A PanCare Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies Nested Case-Control Study

Radiation to the bone and exposure to alkylating agents increases the risk of bone cancer among survivors of childhood cancer, but there is uncertainty regarding the risks of bone tissue radiation ...
openheart.bmj

Long-term stress conditions and out-of-hospital cardiac arrest risk: a nested case–control study

Objective Patients with stress-related disorders and anxiety are at increased risk of developing cardiovascular disease. However, the risk of out-of-hospital cardiac arrest (OHCA) is scarcely ...
Frontiers

Serum microcystin-LR levels and risk of gestational diabetes mellitus: A Chinese nested case-control study

A prospective nested case-control study was performed in the Hunan Provincial Maternal and Child Health Hospital (HPMCHH) in South China. A total of 119 patients with GDM and 238 controls were ...