Leslie Charleson, the soap-opera legend who played Monica Quartermaine on 'General Hospital' starting in the 1970s, died Sunday. She was 79.

Leslie Charleson, who played popular character Dr. Monica Quartermaine for almost 50 years on “General Hospital,” has died, the program’s executive producer announced on Sunday.

Actress Leslie Charleson is dead at the age of 79. Costars are mourning the passing of the longtime General Hospital star who played Dr. Monica Quartermaine.

Charleson was one of the longest serving members of the General Hospital cast, having starred in a whopping 2,079 episodes between 1977 and 2023. She previously described the environment on set as “hostile” in those early days, noting the actress before her had been “rudely fired,” per Soap Opera Digest.

General Hospital ’s longest recurring actor and portrayer of matriarch Monica Quartermaine, Leslie Charleson, has died at 79. Since the show’s executive producer Frank Valentini shared the news on Sunday, fans and fellow cast members have shared their reactions to the significant loss.

Soap opera veteran Leslie Charleson, who played Monica Quartermaine on "General Hospital," has died at the age of 79.

Soap opera icon Leslie Charleson, best known as Monica Quartermaine on "General Hospital," died Sunday morning after a long illness. She was 79.

Leslie Charleson, whose Dr. Monica Quartermaine was the longest-tenured character on “General Hospital,” has died. She was 79. Charleson died of complications from a long illness, said ABC News, which broadcasts the long-running soap opera.

Colleagues are remembering the soap opera star for her "quick wit" and presence on set. She died after a long illness.

Leslie Charleson, who played cardiologist Monica Quartermaine on "General Hospital" for five decades, has died, according to the soap opera's producer. She was 79.

Longtime "General Hospital" star Leslie Charleson has died at 79, the show's executive producer Frank Valentini shared in a statement.