Insulin, the most effective compound for reducing BGLs was discovered in 1922 [7]. Human insulin, a peptide hormone, is synthesised by the β-cells in the pancreatic islets of Langerhans in response to ...

20250002New Data from a Round, Deep Basin in the Russian Heartland: The Smerdyachee Basin as a Prospective Impact Crater 20250003A Tunguska Sized Airburst Destroyed Tall el-Hammam a Middle Bronze Age ...

Asthma and CVDs are globally prevalent conditions with well-established epidemiological links. Type 2 inflammation, characterized by dominant T H 2 cell responses, eosinophil activation, and ...

Abstract We present evidence that Tall el-Hammam, a fortified Middle Bronze Age city in the Jordan Valley, was destroyed by an extraordinary high-energy event in approximately 1650 BCE. Excavations ...

317Boosting pancreatic cancer chemotherapy by disrupting nerve–cancer crosstalk 321Sarcopenic obesity: prospects of mitochondrial transplantation to combat metabolic deterioration in aging ...

Methods: Second-generation Nectin4-targeted VHH-CAR-T cells were constructed and the specific killing efficacy was determined against BLCA cells in vitro. VHH Nectin4-CAR lentivirus was transduced ...

Abstract Silver nanoclusters (AgNCs) have emerged as highly adaptable nanomaterials with vast potential in theranostic applications, by integrating therapeutic and diagnostic capabilities within a ...

Study Design and Population This single-center, hospital-based, retrospective cohort investigation explored the correlation between post-PCI OFR and cardiovascular prognoses among patients with CAD.

Abstract The dedication to enhancing the inclusion of students with disabilities has led to the growing prevalence of assistive technology (AT) in education. The present paper aims to systematically ...

Abstract Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 ...

980Chronic Kidney Disease and Cognitive Dysfunction after Cardiac Surgery 981Catheter Ablation as the First-Line Therapy for Atrial Fibrillation: Update on Evidence and Clinical Implications ...

Introduction Radiation therapy has revolutionized oncology, by enabling precise targeting and treatment of cancer cells. However, its adverse effects on adjacent non-cancerous tissues, particularly ...