Objectives Granulocyte-macrophage colony-stimulating factor (GM-CSF) is implicated in pathogenesis of giant cell arteritis. We evaluated the efficacy of the GM-CSF receptor antagonist mavrilimumab in ...

15 Amsterdam Rheumatology and Immunology Centre, Reade, Amsterdam, The Netherlands Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid ...

Centre for Rheumatology, Department of Medicine, University College London, London, UK Correspondence to: Professor D A Isenberg Centre for Rheumatology, The Middlesex Hospital, University College ...

Background: AR882 is a novel, potent and selective uric acid transporter 1 (URAT1) inhibitor in Phase 2 development for the treatment of hyperuricemia and gout. In Phase 1 healthy subject studies, ...

1 Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, ...

The goal of the Bone and Joint Decade is to improve the health related quality of life for people with musculoskeletal disorders throughout the world. Musculoskeletal disorders are the most common ...

10 Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, USA 11 Department of Rheumatology, University of California at Los Angeles, Los Angeles, California, USA 12 ...

The increased information provided by modern imaging has led to its more extensive use. Our aim was to develop evidence-based recommendations for the use of imaging in the clinical management of the ...

Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan Correspondence to Dr Takehiko Matsushita, Department of Orthopaedic Surgery, Kobe University Graduate ...

The development of articular manifestations in the course of chronic urticaria or in urticarial vasculitis has been widely reported. It is not completely clear, however, whether common pathogenetic ...

Correspondence to Dr Zachary Scott Wallace, Division of Rheumatology, Allergy, and Immunology and Clinical Epidemiology Program, Mongan Institute, Department of Medicine, Massachusetts General ...

Department of Immunology and Transfusion Medicine, Ullevaal University Hospital, Oslo, Norway Correspondence to: Dr J Kjeldsen-Kragh, Department of Immunology and Transfusion Medicine, Ullevaal ...