The advent of single-cell omics technologies has revolutionized our understanding of the complex cellular landscape in cancer. Traditional bulk sequencing ...
A single genetic mutation in a lung cell can start rewriting the rules for the tissue around it almost immediately, ...
In the past decade, immune checkpoint inhibitors (ICIs) have dramatically changed cancer treatment, significantly improving ...
Resistant and severe hypertension represent a growing global health burden and are associated with a markedly increased risk of cardiovascular, renal, and ...
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but can cause immune‑mediated hepatotoxicity (IMH), a potentially serious ...
Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...
Researchers found sex-specific gene expression networks linked to Alzheimer’s pathology using single-cell and systems-level ...
A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
A Cell Perspective argues that generative AI models could help tackle cancer’s multiscale, multimodal complexity by ...
The ventral tegmental area (VTA) is a key site for opioid actions, and emerging evidence suggests that pain states and opioid experience both induce transcriptional, molecular, and circuit adaptations ...
Combining microchip engineering techniques with cutting-edge gene profiling, scientists at Columbia University have developed ...
Target identification is the first and perhaps most critical step in drug discovery and development. Although the human genome contains roughly 20,000 protein-coding genes, only about 4,500 are ...