Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but can cause immune‑mediated hepatotoxicity (IMH), a potentially serious ...
The ventral tegmental area (VTA) is a key site for opioid actions, and emerging evidence suggests that pain states and opioid experience both induce transcriptional, molecular, and circuit adaptations ...
Combining microchip engineering techniques with cutting-edge gene profiling, scientists at Columbia University have developed ...
Target identification is the first and perhaps most critical step in drug discovery and development. Although the human genome contains roughly 20,000 protein-coding genes, only about 4,500 are ...
The field of lung cancer research has increasingly turned its attention to the tumor immune microenvironment (TIME) in non-small cell lung cancer (NSCLC), ...