The embryonic receptor "Smoothened" regulates dopamine and acetylcholine timing to control learning and habit formation in ...

Researchers discovered that suppressing BMP signaling in astrocytes reduces seizures and restores brain balance in Fragile X syndrome models.

Glioblastoma remains a highly challenging malignancy with a pronounced tendency for recurrence. The hypoxic microenvironment ...

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the ...

A signaling pathway best known for shaping the brain before birth also helps govern how adults learn, adapt, and persist in ...

Using single-nucleus RNA sequencing, the authors map transcriptional changes in the rat ventral tegmental area following chronic inflammatory pain and acute morphine exposure. Notably, their ...

Serotonin from antidepressants may amplify tinnitus, offering insight into why ear ringing can worsen during treatment.

BBO-10203 physically and allosterically disrupts the interaction between RAS and PI3Kα, leading to signaling inhibition without inhibiting the ...

Today, the Company presented results from a Phase 2b dose-ranging and proof of concept study of elismetrep, a novel TRPM8 ...

Lung immune diseases have become a major global public health burden, with incidence increasing over the past two decades—especially in industrialized ...