Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps. First, a multiple sequence alignment (MSA) is computed. Then, a tree is reconstructed assuming the ...
This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...
In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...
Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...
Today HPC startup Optalysys announced the successful completion of the Genetic Search System (GENESYS) project with the Earlham Institute. The GENESYS project, which was granted £0.5m in funding from ...
In the beginning, there was Needleman-Wunsch, which begat Smith-Waterman, which begat FASTA, which begat BLAST, and so on. Peel away the information technology jargon surrounding these alignment ...
In a new article, researchers explain their work on computer-assisted approaches towards surveillance and consequent design of drugs and vaccines to combat the growth and spread of the Zika virus. The ...
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