The hidden Markov model (HMM), a statistical model widely applied in machine learning, has proven effective in addressing various problems in ...

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

In bioinformatics, multiple sequence alignment (MSA) is an NP-hard problem. Nature-inspired approaches can provide an approximate solution compared to conventional approaches. In this article, the MSA ...

Proteins, with their extraordinary diversity of structure and function, pose some of the toughest problems in the field of bioinformatics, giving rise to a growing arsenal of computational tools for ...

Conserved sequence motifs within intrinsically disordered protein regions act as evolutionary units that support phase separation and membraneless organelle formation.

MOUNT KISCO, N.Y.--(BUSINESS WIRE)--Softberry, Inc. announces release of a comprehensive set of biomedical research-oriented software applications for academic users to install and run locally on a ...