Abstract: The Nelder-Mead simplex method is a well-known algorithm enabling the minimization of functions that are not available in closed-form and that need not be differentiable or convex.

Need something new to watch on Netflix for Valentine's Day? If you want something a little hotter to watch with your partner, you have to stop scrolling through the same "safe for work" rom-coms ...

IOD distinguishes itself as scientific home for researchers working at the boundaries of traditional academic spheres, and generating growing programs in the integration of research with informatics ...

Abstract: The simplex method, as proposed by Dantzig in 1947, is a widely-used practical algorithm for solving Linear Programs (LPs)—systems of linear inequalities headed by a single linear objective ...

Whole slide images (WSIs) classification represents a fundamental challenge in computational pathology, where multiple instance learning (MIL) has emerged as the dominant paradigm. Current ...