ESMs, a proteome-scale framework to classify loss-of-function missense variants into distinct mechanistic groups by combining two complementary state-of-the-art machine learning models. The strength ...

Physics-based ML framework designs IDPs—biomolecules without fixed structures that underlie key functions and diseases such as Parkinson’s.

Researchers developed machine-learning models to predict visual acuity in patients with high myopia. A cohort study of 967 patients was used to evaluate the models. The results show that a regression ...