Lupus Science & Medicine

Association of disease-modifying antirheumatic drug selection with hospitalised infection among youth with childhood-onset systemic lupus erythematosus

Objective Youth with childhood-onset SLE (cSLE) have increased risk of serious infection. It is unknown how much of this risk ...
eLife

Importance of higher-order epistasis in protein sequence-function relationships

In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
The BMJ

Use of new CORE risk score to predict 10 year risk of liver cirrhosis in general population: population based cohort study

Objective To develop and validate a novel risk prediction model for incident major adverse liver outcomes (MALO) in a primary care setting. Design Population based cohort study. Setting Sweden, with ...
RMD Open

Patients with systemic lupus erythematosus (SLE) have an increased bisphenol A methylation score linked to SLE risk genes and selected clinical subphenotypes

Objectives Bisphenol A (BPA), a xenoestrogen that can alter DNA methylation status, has been implicated in the pathogenesis ...
Investopedia

Weighted Average: Definition and How It Is Calculated and Used

Michael Boyle is an experienced financial professional with more than 10 years working with financial planning, derivatives, equities, fixed income, project management, and analytics. Suzanne is a ...