Users Swear By This Free Adobe Photoshop Alternative

The Affinity desktop application offers professional grade photo editing with vector, pixel, and layout studios similar to ...
Windows Report

Microsoft Adds AI-Powered Alt Text to Word and PowerPoint

Word and PowerPoint now use generative AI to create richer, more contextual alt text on demand, improving accessibility for ...
OMG! Ubuntu

GIMP 3.2 Hits Release Candidate with Improved Text Editing + More

New release candidate splash screen A release candidate of the upcoming GIMP 3.2 release is now available for download and ...
eLife

Multi-barrier unfolding of the double-knotted protein, TrmD–Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

This study investigates the folding and unfolding behavior of the doubly knotted protein TrmD-Tm1570, providing insight into the molecular mechanisms underlying protein knotting. The findings reveal ...
eLife

Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a ...