Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...
The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can ...
Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...
The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...
Recent advancements in mass spectrometry and computational tools enhance the feasibility of top-down proteomics. Top-down ...
A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider. MtoZ Biolabs leverages advanced LC-MS/MS to characterize histone post-translational modifications. BOSTON, MA, ...
HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing ...
A new study has decoded how pea plants respond to salt stress through precise epigenetic reprogramming. Researchers created the first genome-wide map of four major histone modifications—H3K4me3, ...
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