The endoplasmic reticulum (ER)-localized transmembrane proteins IRE1, PERK and ATF6 detect the load of unfolded protein in the lumen of the organelle, serving as stress receptors. They transduce the ...
1 Centre for Exercise and Sport Science, Deakin University, School of Exercise and Nutrition Sciences, Burwood, Victoria, Australia 2 Centre for Physical Activity and Nutrition Research, Deakin ...
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