CCNs are a family of extracellular matrix proteins that regulate diverse aspects of cellular functions, and are involved in inflammation and tissue repair. Deregulation of CCN proteins is associated ...

The matrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases that consist of more than 21 human MMPs and numerous homologues from other species. They can be divided into ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from its microenvironment. Created by integrating six different imaging ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

Tissue engineering and regenerative medicine have made remarkable strides in developing strategies to repair and regenerate tissues affected by disease, ...

We applied swim flume-mediated exercise during zebrafish caudal fin regeneration to explore mechanical loading impacts on a robust model of organ regeneration. Exercise initiated during but not after ...

FKBP65 (65-kDa FK506-binding protein) is an endoplasmic reticulum (ER)-localized peptidyl-prolyl cis-trans isomerase predicted to play a role in the folding and trafficking of secretory proteins. In ...

Scientists say the origins of the ‘Hippo pathway’ date back to single-celled organisms In A Nutshell The Hippo signaling ...