Alzheimer's disease is marked by the buildup of amyloid plaques in the brain, but most ways of studying these deposits in mouse models require sacrificing the animals. That limits researchers' ability ...

A team led by scientists at Harvard Medical School, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard used CRISPR technology to pinpoint genes that could be edited to boost ...

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered ...

Combining a plaque-binding fluorescent dye with flat and tapered optical fibers enables depth-resolved monitoring across brain regions during natural behavior, offering a minimally invasive way to ...