RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

During elongation, the new RNA strand becomes longer and longer as the DNA template is transcribed. In this view, the 5' end of the RNA strand is in the foreground. Note the inclusion of uracil (yello ...

Previous biochemical studies of the BLM gene product have shown its ability in conjunction with topoisomerase lllα to resolve double Holliday structures through a process called "dissolution." This ...