Frontiers

MAPK Pathway Cross-talk in Cancer Therapy Resistance

Mitogen-Activated Protein Kinase (MAPK) pathways are crucial signaling routes that mediate multiple cellular processes, ...
CU Boulder News & Events

Multiple cancers escape from multiple MAPK pathway inhibitors and use DNA replication stress signaling to tolerate aberrant cell cycles (Science Signaling 2023)

Many cancers harbor pro-proliferative mutations of the mitogen-activated protein kinase (MAPK) pathway. In BRAF-driven melanoma cells treated with BRAF inhibitors, subpopulations of cells escape ...
JSTOR Daily

IN VITRO AND IN VIVO EFFECT OF MAPK SIGNAL TRANSDUCTION PATHWAY INHIBITORS ON ECHINOCOCCUS MULTILOCULARIS

To evaluate the effect of mitogen-activated protein kinase (MAPK) signal transduction pathway inhibitors against alveolar echinococcosis in vitro and in vivo, Echinococcus multilocularis metacestode ...
News-Medical.Net on MSN

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health ...