We describe and contrast several different bootstrap procedures for penalized spline smoothers. The bootstrap methods considered are variations on existing methods, developed under two different ...

Research in the field of nonparametric shape constrained regression has been intensive. However, only few publications explicitly deal with unimodality although there is need for such methods in ...

Single nucleotide polymorphism (SNP) interaction plays a critical role for complex diseases. The primary limitation of logistic regressions (LR) in testing SNP–SNP interactions is that coefficient ...

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