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As a doctor of physical therapy, I work with clients every day who are dealing with pain. The pain-medicine industry might tell you there are endless ways to re ...
A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...
DHA has previously been shown to inhibit voltage-dependent Ca 2+ channels (VDCCs). The research group found a new pharmacological action of DHA to inhibit the Orai1 channel, which is one of ...
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Do warm-ups improve muscle strength?
Increasing muscle temperature through warm-ups enhances contractile function and power, but maximum force remains unchanged, ...
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Compound found in rice bran can suppress intestinal contractions by inhibiting calcium influx
A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...
Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...
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Scientists reveal how a key inflammatory molecule triggers esophageal muscle contraction
A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth ...
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