Boston-based Dana-Farber Cancer Institute has launched the Center for RAS Therapeutics, aiming to study and develop drug therapies for RAS-driven cancers. RAS gene mutations are found in 20% of all ...

Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their ...

SALT LAKE CITY—Cells with a mutation in the gene called K-Ras—found in close to 30 percent of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung ...

Researchers at the National Institutes of Health (NIH) and their collaborators have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their ...

National Institutes of Health (NIH) scientists and collaborators say they have discovered a new way in which RAS genes, commonly mutated in cancer, may drive tumor growth beyond their well-known role ...

A single oncogenic mutation can hijack mechanisms causing benign tumors to become malignant. A study by researchers at Rockefeller University (NY, USA) finds that a single mutated gene in cancer stem ...

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS and a key ...

Figure 3: Various scaffolds utilized to engineer binders to Ras and their binding epitopes. Ras proteins are small GTPases that regulate cell growth and division. Mutations in Ras genes are associated ...

Find a tumor in a human or rodent, and the chances are that lurking within it will be an activated ras gene. The cancer-police have been trailing it for the better part of two decades and the file of ...

Researchers have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling at the cell surface. Mutant RAS, they ...