St. Jude Children's Research Hospital scientists have identified a promising combination approach to treat a rare but ...

Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney Kimmel ...

All tissues are not equally sensitive to radiation. It has long been recognized that the well-known tumor suppressor protein and transcription factor p53 is linked to the degree of a tissue’s ...

Researchers at The University of Texas MD Anderson Cancer Center have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact through the CREB1 protein to ...

“Our results provide unique insights into the mechanism of action of PG3 as a novel cancer therapeutic targeting p53 pathway-like tumor suppression” As highlighted in the abstract of this study, ...

Wistar Institute scientist Maureen Murphy wants to solve a decades-long mystery: Why is ovarian cancer often resistant to hormone therapy? In a recently published study, she shared a new theory as to ...

December 16, 2025) St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a ...

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 ...

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage ...