Nearly 25 years after scientists completed a draft human genome sequence, many of its 3.1 billion letters remain a puzzle. The 98% of the genome that is not made of protein-coding genes — but which ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

New research from the Wisconsin Institute for Discovery is tackling a complex packing problem. Thanks to the development of a powerful new computational tool introduced in a study published earlier ...

The accumulation of mutations in DNA is often mentioned as an explanation for the aging process, but it remains just one ...

Vast swathes of the human genome remain a mystery to science. A new AI from Google DeepMind is helping researchers understand how these stretches of DNA impact the activity of other genes. While the ...

The puzzle seems impossible: take a three-billion-letter code and predict what happens if you swap a single letter. The code we’re talking about—the human genome—stores most of its instructions in ...

DNA holds our genetic blueprints, but its cousin, RNA, conducts our daily lives I n 1957, just four years after Francis Crick ...