In a small clinical trial, customized mRNA vaccines against high-risk skin cancers appeared to reduce the risk of cancer ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...

The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...

Vaccines using mRNA technology have been studied for decades, experts say. Over the last several days, the safety and efficacy of messenger RNA, or mRNA, vaccines have come under intense scrutiny. On ...

Messenger Ribonucleic Acid (mRNA) vaccines gained global recognition during the Coronavirus Disease 2019 (COVID-19) pandemic, proving their value through rapid development, high efficacy, and broad ...

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine—which designs nanotechnology-based ...

With the U.S. Health and Human Services Secretary Robert F. Kennedy, Jr. canceling nearly $500 million in mRNA vaccine research contracts on Tuesday, you may be wondering if mRNA vaccines are safe.

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...