Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

Transfer RNAs (tRNAs) deliver specific amino acids to ribosomes during translation of messenger RNA into proteins. The abundance of tRNAs can therefore have a profound impact on cell physiology, but ...

There are different kinds of ribonucleic acids that play essential roles in many aspects of molecular biology, including the creation of proteins from gene sequences in DNA. One type of ribonucleic ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Rare diseases, defined by FDA as “a disease or condition that affects less than 200,000 people in the United States” (1), may ...

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are ...

(A) Suppressor tRNA readthrough strategy. Natural tRNAs with engineered anticodons are charged with canonical amino acids to enable readthrough of the premature termination codon (PTC). (B) Unnatural ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...