Christian McCaffrey accomplished a milestone he hasn't pulled off since 2023 during the 49ers' matchup against the Colts on Monday night.

San Francisco 49ers running back Christian McCaffrey made his fantasy football owners happy on Monday night. He is also now close to breaking a Super

The San Francisco 49ers put up a ton of points on Monday night, with a ton of production from their star players, and with Week 16 being the fantasy football playoff semifinals in most leagues, it potentially swung a lot of matchups in a different direction.

Christian McCaffrey breaks down why the 49ers’ offense is so difficult to defend as San Francisco’s playoff push continues.

TE George Kittle says Christian McCaffrey has "years left in the tank" as the San Francisco star delivers another dominant NFL season.

Indianapolis’ long-ball threat is leading the league in yards per catch entering Week 16, averaging 20.1 YPC on the year, nearly eclipsing his PrizePicks prop in just one catch on average. The Colts offense should find greater success through the air,

San Francisco 49ers tight end George Kittle grabs a 17-yard pass from quarterback Brock Purdy. San Francisco 49ers kicker Eddy Piñeiro makes a 25-yard field goal. San Francisco 49ers wide receiver Kendrick Bourne secures $500,000 contract bonus after 11-yard gain following a pass from quarterback Brock Purdy.

The San Francisco 49ers had four offensive stars and two special-teams players selected to the 2026 NFL Pro Bowl.