Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies ...

Once HIV infects a cell, the virus inserts its genetic information into the DNA, making the infection generally incurable.

Harmful genetic changes in sperm become substantially more common as men age because some are actively favored during sperm ...

Harmful genetic changes in sperm become substantially more common as men age because some are actively favored during sperm ...

Explore the latest advancements in liquid biopsy for oncology, examining current trends and insights that could shape future ...

After decades of fixating on mutations in nuclear DNA as the prime suspects in cancer development, researchers are increasingly peering into the cell’s powerhouse for clues. Mutations in mitochondrial ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

About 80% of orange cats are males, including the four orange cats owned by the Short Wave team: Zuko, Benny, Tang and Dorito. Scientists have long suspected that their orange color was a sex-linked ...

Junk DNA” may hold the key to treating tough cancers. Existing drugs exploit weaknesses in cells with gene mutations. Researchers at King’s College London have identified a promising strategy for ...

G4 and R-loop signals at the indicated genomic locus. Both G4s and R-loops accumulate in cells where the resolution of G4 knots is defective (red). Not all DNA looks like the familiar twisted ladder.

When a key protein regulator dials down DNA repair mechanisms, our cells accumulate more mutations, which may cause us to age ...