Until recently, little was known about how transposable elements contribute to gene regulation. These are little pieces of DNA that can replicate themselves and spread out in the genome. Although they ...
A new study shows that transposable elements play an important role in regulating genetic expression with implications to advance the understanding of genetic evolution. Until recently, little was ...
Researchers in Michigan published a study “Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes” in Nature Communications that shows ...
The discovery in maize of jumping genes, also known as transposable elements, revolutionised our perception of genome organisation across kingdoms. Transposable elements are mobile small repetitive ...
Mammalian genomes have been colonised by transposable elements (TEs), so called ‘genetic parasites’, which occupy ~ 50% of genomic DNA and harbour the potential to propagate, resulting in genetic ...
An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Molecular-Level Dissection ...
Whole-genomic sequencing has revolutionized the amount and detail of genetic diversity now available to researchers to study. While the researchers previously had looked at a few hundred mobile ...
The MuDR/Mu transposons of maize are the most aggressive DNA transposons known in terms of their ability to increase the forward mutation frequency by ~ 100-fold. Their activities are held in check by ...
New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors ...
For decades, large stretches of human DNA were dismissed as "junk" and considered to serve no real purpose. In a new study published in Cell Genomics, researchers at Lund University in Sweden show ...
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