With support from the National Institutes of Health, the COBRE Center for RNA Biology in Health and Disease will create a ...

This whitepaper highlights a ligation-based workflow that enhances gRNA purity and yield, delivering consistent performance for demanding genome editing applications.

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

It's no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire ...

SANTA CRUZ — A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, has created an innovative software program called CRISPRware, ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...