For the last half-century, the dominant explanation for depression has centered on serotonin. The basic idea: low levels of brain serotonin or serotonin activity leads to symptoms of depression. This ...

When someone you care about seems off, it’s only natural to worry about them. Maybe you've noticed that they’re not quite themselves lately—they’re more withdrawn, easily irritated, or just feeling ...

You’d be forgiven for thinking that depression has a simple explanation. The same mantra — that the mood disorder comes from a chemical imbalance in the brain — is repeated in doctors’ offices, ...