For the last half-century, the dominant explanation for depression has centered on serotonin. The basic idea: low levels of brain serotonin or serotonin activity leads to symptoms of depression. This ...

You’d be forgiven for thinking that depression has a simple explanation. The same mantra — that the mood disorder comes from a chemical imbalance in the brain — is repeated in doctors’ offices, ...

For decades, researchers have developed and tested adolescent depression prevention programs that show strong results. But a new study reveals a major flaw in the evidence base: These programs, ...