HIV type I (HIV-1) can cause G₂ cell cycle arrest and death of CD4⁺ T lymphocytes in vitro and inexorable depletion of these cells in vivo. However, the molecular mechanism of viral cytopathicity has ...
Since the first cases of AIDS were identified in 1981, this disease has led to the death of >20 million people. Despite remarkable medical advances, the incidence of HIV-1 infections continues to rise ...
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