The pharmacokinetics of fentanyl by the intravenous route can be described by a 2-compartment model in this patient group, and using this study design. The clearance of fentanyl was approximately 1.5 ...
High- and Low-Dose Interferon Alfa-2b in High-Risk Melanoma: First Analysis of Intergroup Trial E1690/S9111/C9190 PURPOSE: To characterize the pharmacokinetics of topotecan in a population model that ...
Twenty-four patients were randomized in the study. Two populations were defined in the protocol: intent-to-treat and per protocol. One patient (no. 16) withdrew from the trial after having received ...
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