A large review of existing research took a hard look at how well the pain pill tramadol actually works for chronic pain.

Objective: To assess the efficacy, safety and impact on quality of life of tramadol in the treatment of neuropathic pain in patients with cancer. Methods: Patients with similar characteristics were ...

Clin Drug Invest. 2005;25(7):435-443. Drug absorption and, therefore, the clinical effects of orally administered drugs strongly depend on their mode of transit through the gastrointestinal tract.

The strong opioid painkiller tramadol is not significantly effective at easing the chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published in ...