Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...
4don MSN
Protein engineering toolset boosts efficacy of CAR-T cells targeting blood and solid cancers
Cancer researchers focused on improving the success of cancer immunotherapies introduced a new tool in a Yale study published ...
Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...
CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in ...
Zeaxanthin, best known for eye health, has been found to boost the tumor-killing power of T cells. Researchers showed it ...
A newly discovered "timekeeper" for fighting infections dramatically shapes the body's immune defenses, offering insight as to why antiviral T cell response varies throughout the day, according to UT ...
In a new study published in GEN’s sister peer-review journal, GEN Biotechnology, titled, “Exploring Structure-Function Relationships in Engineered Receptor Performance Using Computational Structure ...
MedPage Today on MSN
Ulcerative Colitis: Next Target for CAR T-Cell Therapy?
The range of autoimmune diseases treatable with chimeric antigen receptor (CAR) T-cell therapy could be much broader than ...
Contrary to public concerns, receiving frequent COVID-19 booster vaccinations will not weaken the immune system, providing reassurance to vulnerable groups facing new variants. Study: No evidence of ...
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