Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

The 2014 Nobel Prize in Chemistry was awarded for the development of super-resolved fluorescence microscopy, including STED (Stimulated Emission Depletion) microscopy. This method can be used to ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues at the frontier of biological research. Professor Xi Peng's group at ...

Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...

Using an approach that combines 3D printing, silicone molding and a UV curable clear resin, researchers fabricated an inexpensive lenslet array, which they used for super-resolution imaging in a ...