We describe the case of identical twin boys who presented with low body weight despite excessive caloric intake. An evaluation of their fibroblasts showed elevated oxygen consumption and decreased ...
First-in-human phase 1-2A study of CB-103, an oral Protein-Protein Interaction Inhibitor targeting pan-NOTCH signalling in advanced solid tumors and blood malignancies. Background: IM156 is a novel ...
Oxidative stress is an imbalance of free radicals and antioxidants in the body that can lead to cell and tissue damage. Evidence suggests that long-term oxidative stress contributes to the development ...
New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role ...
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Johns Hopkins study reveals enzyme that shields neurons from oxidative stress
New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the ...
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