Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

The structure of a protein is crucial in determining its functionality and is much more conserved than sequence during evolution. A key task in structural biology is to compare protein structures to ...

Roestel, Jessica A., Wiersema, John H., Jansen, Robert K., Borsch, Thomas, and Gruenstaeudl, Michael. 2023. [Dataset] On the importance of correct DNA sequence alignment in plastid phylogenomics – an ...