Bcl-2 family regulation of neuronal cell fate plays an important role in normal mammalian nervous system development and in determining the pathological consequences of neurotoxic stimuli. However, a ...
ssDNA, which is involved in numerous aspects of chromosome biology, is managed by a suite of proteins with tailored activities. The majority of these proteins bind ssDNA indiscriminately, exhibiting ...
Researchers have found a switch that regulates the activity of HNF1A, a gene that causes diabetes. The study highlights potential new vulnerabilities in the disease and could lead to the development ...
David R. Amici, Daniel J. Ansel, Kyle A. Metz, Roger S. Smith, Claire M. Phoumyvong, Sitaram Gayatri, Tomasz Chamera, Stacey L. Edwards, Brendan P. O’Hara, Shashank ...
A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Scientists have identified a mechanism that helps T cells find that ...
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