Bcl-2 family regulation of neuronal cell fate plays an important role in normal mammalian nervous system development and in determining the pathological consequences of neurotoxic stimuli. However, a ...

ssDNA, which is involved in numerous aspects of chromosome biology, is managed by a suite of proteins with tailored activities. The majority of these proteins bind ssDNA indiscriminately, exhibiting ...

Researchers have found a switch that regulates the activity of HNF1A, a gene that causes diabetes. The study highlights potential new vulnerabilities in the disease and could lead to the development ...

A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Scientists have identified a mechanism that helps T cells find that ...