Binding of renin to this receptor increases the catalytic activity of renin by about four- to fivefold. Furthermore, prorenin, which does not exhibit significant ability to generate angiotensin I (ang ...

Introduction Physiology of the Renin-Angiotensin-Aldosterone System and Its Pathophysiologic Role in Some Forms of Hypertension Renin in the Selection of Antihypertensive Drug Therapy Renin as a ...

Angiotensinogen is produced mainly in the liver and fat cells, in response to poor perfusion, and acts as a pro-signal in the complex downstream renin–angiotensin–aldosterone (RAAS) system.

Initial evidence of the existence of renin, which is an angiotensinogenase enzyme secreted by the kidney, was presented to the medical community more than 100 years ago. Nevertheless, the significance ...

When you have high blood pressure, also called hypertension, finding the reason for it can help you get the right treatment. A renin test can shed light on what’s happening in your body. Your doctor ...

A potential association between the use of angiotensin-receptor blockers (ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus disease 2019 (Covid-19) has not been well ...

[Updated]-- The European Medicines Agency said last week that it was initiating a review of the combined use of agents that block the renin-angiotensin system (RAS). The three classes of RAS-blocking ...