Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Scientists say their new insights into how a key brain protein works could help resolve a long-standing question in molecular neuroscience. Researchers supported by the National Institutes of Health a ...

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...

Researchers at Karolinska Institutet have identified small molecules capable of influencing a hard-to-target receptor family ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...

Erythropoietin, the protein that drives red blood cell formation, also induces tolerance in dendritic cells, leading to the ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant ...