What Are Clinical Trials, and How Do They Work?

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us.
ascopubs.org

A phase 2 multicenter, open-label, randomized, controlled trial in patients with stage II/III colorectal cancer who are ctDNA positive following resection to compare efficacy ...

Myopenia and mechanisms of toxicity in older adults with colorectal cancer (CRC): The M&M study (WF-1806). Background: Colorectal cancer (CRC) is one of the most commonly occurring cancers with high ...
ascopubs.org

Becotatug vedotin vs. chemotherapy in pre-heavily treated advanced nasopharyngeal carcinoma: A randomized, controlled, multicenter, open-label study.

PD-1 blockade with toripalimab incorporated into induction chemotherapy and radiotherapy with or without concurrent cisplatin in locoregionally advanced nasopharyngeal carcinoma (DIAMOND): A ...
STAT

Keeping pregnant participants out of medical research is more dangerous than including them

“Well, we don’t have as much evidence as we would like on steroid use during pregnancy,” the obstetrician warned my co-author, Natalia Emanuel, as she wrote a prescription for inhaled corticosteroids ...
AHA/ASA Journals

Triple Versus Dual Lipid-Lowering Therapy in Acute Coronary Syndrome: The ES-BempeDACS Randomized Clinical Trial

BACKGROUND: Current guidelines recommend a stepwise strategy to achieve low-density lipoprotein cholesterol (LDL-C) goals after acute coronary syndrome (ACS). Earlier intensive strategies based on a ...