Nearly 1 in 30 clinical trials were interrupted by funding cuts to the National Institutes of Health, affecting more than ...

Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us.

Clinical trials are more connected and more closely examined than ever. Inspection readiness isn’t a last-minute document ...

Randomised clinical trials (RCTs) remain the gold standard in evaluating therapeutic interventions, ensuring that treatment effects are not confounded by systematic errors. Central to these trials is ...

Immunocore announces randomization of first patient in the global, registrational Phase 3 clinical trial testing brenetafusp for the treatment of first-line advanced or metastatic cutaneous melanoma ...

The S2302 Pragmatica-Lung trial, led by the SWOG and run through the National Cancer Institute's National Clinical Trials Network, is a pragmatic registrational-intent study for advanced non–small ...

"Covariate adjustment" in the randomized trial context refers to an estimator of the average treatment effect that adjusts for chance imbalances between study arms in baseline variables (called ...

The ongoing EPIC clinical trial is the first randomized head-to-head comparison of two neonatal Fc receptor (FcRn)-targeting ...

Paul Meier, the statistician who revolutionized clinical trials in the United States, died last Sunday (August 7) from complications following a stroke, according to the New York Times. He was ...

The SOL-R registrational trial (NCT06495918) of OTX-TKI (AXPAXLI) by Ocular Therapeutix has reached its randomization target of 555 patients.

(OXFORDSHIRE, England & CONSHOHOCKEN, Penn. & ROCKVILLE, Md., US, 18 June 2024) Immunocore Holdings plc (Nasdaq: IMCR) (“Immunocore” or the “Company”), a commercial-stage biotechnology company ...