The inhibition of HIV-1’s replicative machinery remains a cornerstone in the battle against AIDS. Central to this approach are inhibitors targeting reverse transcriptase (RT) and integrase. Reverse ...
Stephen Goff is the Higgins Professor of Biochemistry at Columbia University in New York City. He was a postdoc in Baltimore’s lab at the Massachusetts Institute of Technology in Cambridge from 1978 ...
Surface model of SpCas9–reverse transcriptase–pegRNA–target DNA complex. The prime editor, composed of a SpCas9 and a reverse transcriptase, reverse transcribes template sequence in pegRNA, resulting ...
Bacteria defend themselves from viral infection using diverse immune systems, many of which sense and target foreign nucleic acids. Defense-associated reverse transcriptase (DRT) systems provide an ...
RNAConnect, a pioneering life science reagent company, has officially launched. The company promises groundbreaking solutions for exploring the real-world diversity of RNA sequence and structure.
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